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The conference "The Expanding Genetic Code and Beyond" will serve as a forum to explore frontiers in the evolving genetic code, nucleic acid editing, synthetic biology and their transformative applications. We will highlight recent advances in genetic code expansion and protein evolution that push the boundaries of precision protein engineering. This meeting will showcase technology's profound impact on life science and health, from dissecting complex biological pathways to developing novel therapeutics. Furthermore, we will explore the exciting potential of synthetic genomes and artificial enzymes for catalysis, highlighting how these technologies are revolutionizing fields ranging from sustainable chemistry to synthetic biology. By bringing together leading experts, this conference aims to foster collaboration and drive innovation, propelling the expanding genetic code and its related technologies towards groundbreaking discoveries and applications.
Peng CHEN, Shenzhen Bay Laboratory, Peking University
Yun GE, Shenzhen Bay Laboratory
Shixian LIN, Zhejiang University
Tao LIU, Peking University
Xiaozhou LUO, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences
Ryan MEHL, Oregon State University
(in alphabetical order)
Keynote Speakers
Jason CHIN, Generative Biology Institute
William DEGRADO, University of California, San Francisco
Jay KEASLING, University of California, Berkeley
Peter SCHULTZ, The Scripps Research Institute
Invited Speakers
Ahmed BADRAN, The Scripps Research Institute
Ned BUDISA, University of Manitoba
Abhishek CHATTERJEE, Boston College
Junbiao DAI, Agricultural Genomics Institute at Shenzhen
Bryan DICKINSON, The University of Chicago
Xue Sherry GAO, University of Pennsylvania
Thomas HUBER, Australian National University
Kathrin LANG, ETH Zürich
Chang LIU, University of California, Irvine
Haiyan LIU, University of Science and Technology of China
Peilong LU, Westlake University
Ryan MEHL, Oregon State University
Gerard ROELFES, University of Groningen
Jiangyun WANG, Institute of Biophysics, Chinese Academy of Sciences
Nanxi WANG, Nanjing University of Chinese Medicine
Yuzhou WU, Huazhong University of Science and Technology
Haifeng YE, East China Normal University
Demin ZHOU, Peking University
Jingyi HOU, EMBO Press
Shushu JIANG, Vita
Yiyun SONG, Nature Chemical Biology
Yingjin YUAN, Tianjin University
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14:00-18:00 |
On-site Registration |
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08:00-08:30 |
On-site Registration |
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08:30-08:35 |
Opening Remarks Peng CHEN, Peking University, Shenzhen Bay Laboratory |
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08:35-09:15 |
Peter SCHULTZ, The Scripps Research Institute TBA |
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09:15-09:40 |
Nediljko BUDISA, University of Manitoba Rewriting the Chemistry of Life: Methodological Frontiers in Genetic Code Expansion |
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09:40-10:05 |
Tao LIU, Peking University TBA |
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10:05-10:35 |
Group Photo & Break |
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10:35-11:00 |
Kathrin LANG, ETH Zürich TBA |
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11:00-11:25 |
Shixian LIN, Zhejiang University TBA |
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11:25-11:50 |
Ryan A. MEHL, Oregon State University TBA |
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11:50-12:15 |
Yuzhou WU, Huazhong University of Science and Technology Expanding the Genetic Code for Engineering Artificial Enzymes |
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13:45-14:25 |
William DEGRADO, University of California, San Francisco De Novo Design of Small Molecule-Binding Proteins and Enzymes |
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14:25-14:50 |
Haiyan LIU, University of Science and Technology of China De Novo Design of Functional Proteins with SCUBA-T |
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14:50-15:15 |
Jiangyun WANG, Institute of Biophysics, Chinese Academy of Sciences TBA |
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15:15-15:40 |
Break |
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15:40-16:05 |
Gerard ROELFES, University of Groningen TBA |
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16:05-16:30 |
Peilong LU, Westlake University De Novo Design of Mirror-Image Protein Binders |
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16:30-16:55 |
Thomas HUBER, Australian National University Illuminating Proteins |
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08:00-08:30 |
On-site Registration |
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08:30-09:10 |
Jason CHIN, Generative Biology Institute TBA |
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09:10-09:35 |
Demin ZHOU, Peking University TBA |
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09:35-10:00 |
Abhishek CHATTERJEE, Boston College Reprogramming Translation in Mammalian Cells |
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10:00-10:20 |
Break |
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10:20-10:45 |
Chang LIU, University of California, Irvine Extensive Biomolecular Evolution in Vivo |
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10:45-11:10 |
Nanxi WANG, Nanjing University of Chinese Medicine Acylation-Mediated Protein Regulation in Medicinal Plants |
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11:10-11:35 |
Bryan DICKINSON, The University of Chicago Harnessing In Vivo Evolution to Decode and Control Molecular Recognition |
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11:35-12:00 |
Xiao XIE, Tsinghua University TBA |
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13:30-14:10 |
Jay KEASLING, University of California, Berkeley TBA |
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14:10-14:35 |
Junbiao DAI, Agricultural Genomics Institute at Shenzhen Machine Learning–Guided Engineering of Yeast eRF1 |
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14:35-15:00 |
Ahmed BADRAN, The Scripps Research Institute Programmable Biosynthesis of New-to-Nature Polymers |
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15:00-15:20 |
Break |
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15:20-15:45 |
Xiaozhou LUO, Shenzhen Institutes of Advanced Technology, CAS TBA |
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15:45-16:10 |
Xue Sherry GAO, University of Pennsylvania Engineering CRISPR Systems for Precision Therapeutics and Molecular Innovation |
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16:10-16:35 |
Haifeng YE, East China Normal University Synthetic Genetic Control Systems for Smart Living Therapeutics |
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16:35-17:35 |
Panel Discussion Jingyi HOU, EMBO Press Shushu JIANG, Vita Yiyun SONG, Nature Chemical Biology Yingjin YUAN, Tianjin University |
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17:35-17:50 |
Closing Remarks and Poster Awards Peng CHEN, Peking University, Shenzhen Bay Laboratory |
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19:00-21:00 |
Module I. Fundamentals of Genetic Code Expansion and Photo‑crosslinking • Historical development, fundamental principles, and key advantages of genetic code expansion • Applications of genetically encoded photocrosslinking and basic principles of crosslinking mass spectrometry analysis |
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10:00-12:00 |
Module II. Incorporation and Characterization of Noncanonical Amino Acids • Plasmid construction and transformation strategies • Selection and site-specific incorporation of noncanonical amino acids (ncAAs) •Protein expression, SDS-PAGE analysis, and mass spectrometric characterization |
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12:00-14:00 |
Break |
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14:00-16:00 |
Module III. Photo‑crosslinking, Chemical Labeling, and Sample Preparation • Photo‑crosslinking of proteins containing photo-crosslinkers • Click chemistry-based labeling and biotin enrichment • Sample preparation workflows for mass spectrometry |
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16:00-16:20 |
Break |
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16:20-18:20 |
Module IV. Mass Spectrometry-Based Identification and Data Analysis • Standard workflows for protein identification • Experimental strategies for crosslinking mass spectrometry • Data analysis software and computational workflows |
This conference will feature a poster presentation session, with an award for outstanding posters. We sincerely invite you to submit your abstract and participate in the poster presentation (encouraging the display of the latest research advancements or unpublished research topics).
How to Participate: Submit abstract for poster when register.
Poster Requirements: If you participate in the poster presentation, please print the poster yourself and bring it to the conference venue to be posted in the designated area by the staff.
Poster Size: Width 80 cm*Height 120cm
Registration Deadline: September 17, 2026
Please click the Register link at the top of this web page to proceed with the registration process.
Registration Fees
*Please upload valid documents for review if you are a student.
Notice
1. When making transfers, please include the following note: GCE + [Your Full Name].
2. Please complete the registration and payment before September 17, 2026. Attendees registering on-site will be provided with only the electronic program.
3. The electronic invoice for the registration fee will be sent to the registered email address within 15 working days after the symposium.
Refund Policy
1. A 2% administrative fee will be charged for all refund transactions.
2. Refund requests submitted after 18:00 (GMT+8) on September 20, 2026 will not be processed.
Email: symposium@smart.org.cn
Tel: +86-173 2236 4121
We do not provide centralized accommodation for this symposium. Participants can arrange their own accommodation by contacting nearby hotels. (If you encounter any difficulty in booking a hotel, please contact us at symposium@smart.org.cn.)
Phishing Alert: Please be alert to fraudulent emails claiming to offer symposium accommodation or hotel services. These phishing attempts may request payment or personal information. If you receive such an email, do not reply, click any links, download attachments, or share any information. We appreciate your vigilance.
1. EVEN Hotels Shenzhen Guangming Cloud Park, an IHG Hotel
Address: No. 98 Zhenyuan Road, Guangming District, Shenzhen
The hotel is 200 meters (~3-minute walk) from the conference venue.
Contact: Mr. Zhou, +86-135 0841 8360
2. Holiday Inn Express Shenzhen Guangming Cloud Park, an IHG Hotel
Address: No. 98 Zhenyuan Road, Guangming District, Shenzhen
The hotel is 200 meters (~3-minute walk) from the conference venue.
Contact: Mr. Zhou, +86-135 0841 8360
3. SYSU Academic Vila, Shenzhen Campus
Address : No.66 Gongchang Road, Guangming District, Shenzhen, Guangdong, China, Guangming District, Shenzhen
The hotel is 2.5 kilometers (~5-minute drive) from the conference venue.
Contact : Mr. Ran, +86-133 3028 2207
4. Guangming CIMC Executive Apartments Hotel
Address: CIMC Executive Apartments Hotel, Qiaoming Road, Fenghuang Street, Guangming District, Shenzhen
The hotel is 7.6 kilometers (~20-minute drive) from the conference venue.
Contact: Mr. Lu, +86-138 2659 2644