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SMART Symposium on the Expanding Genetic Code and Beyond & GCE Workshop
Register
Date
September 21-23, 2026
Registration Deadline
September 17, 2026
Venue
Cloud Park International Conference Center, Shenzhen, China
About
Organizers
Confirmed Speakers
Panel Discussion Chairs
Program
GCE Workshop
Poster Session
Registration
Contact Us
Accommodation
About

The conference "The Expanding Genetic Code and Beyond" will serve as a forum to explore frontiers in the evolving genetic code, nucleic acid editing, synthetic biology and their transformative applications. We will highlight recent advances in genetic code expansion and protein evolution that push the boundaries of precision protein engineering. This meeting will showcase technology's profound impact on life science and health, from dissecting complex biological pathways to developing novel therapeutics. Furthermore, we will explore the exciting potential of synthetic genomes and artificial enzymes for catalysis, highlighting how these technologies are revolutionizing fields ranging from sustainable chemistry to synthetic biology. By bringing together leading experts, this conference aims to foster collaboration and drive innovation, propelling the expanding genetic code and its related technologies towards groundbreaking discoveries and applications.

Organizers

Peng CHEN, Shenzhen Bay Laboratory, Peking University

Yun GE, Shenzhen Bay Laboratory

Shixian LIN, Zhejiang University

Tao LIU, Peking University

Xiaozhou LUO, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences

Ryan MEHL, Oregon State University‬‬

Confirmed Speakers

(in alphabetical order)

 

Keynote Speakers

Jason CHIN, Generative Biology Institute 

William DEGRADO, University of California, San Francisco

Jay KEASLING, University of California, Berkeley

Peter SCHULTZ, The Scripps Research Institute

 

Invited Speakers

Ahmed BADRAN, The Scripps Research Institute

Ned BUDISA, University of Manitoba

Abhishek CHATTERJEE, Boston College

Junbiao DAI, Agricultural Genomics Institute at Shenzhen

Bryan DICKINSON, The University of Chicago

Xue Sherry GAO, University of Pennsylvania

Thomas HUBER, Australian National University

Kathrin LANG, ETH Zürich

Chang LIU, University of California, Irvine

Haiyan LIU, University of Science and Technology of China

Peilong LU,  Westlake University

Ryan MEHL, Oregon State University

Gerard ROELFES, University of Groningen

Jiangyun WANG, Institute of Biophysics, Chinese Academy of Sciences

Nanxi WANG, Nanjing University of Chinese Medicine

Yuzhou WU, Huazhong University of Science and Technology

Haifeng YE, East China Normal University

Demin ZHOU, Peking University

Panel Discussion Chairs

Jingyi HOU, EMBO Press

Shushu JIANG, Vita

Yiyun SONG, Nature Chemical Biology

Yingjin YUAN, Tianjin University

Program
September 20
September 21
September 22
Show All
Day 0
14:00-18:00

14:00-18:00

On-site Registration

Day 1
08:00-20:00

08:00-08:30

On-site Registration

08:30-08:35

Opening Remarks 

Peng CHEN, Peking University, Shenzhen Bay Laboratory

Session I
08:35-12:15

08:35-09:15

Peter SCHULTZ, The Scripps Research Institute

TBA     

09:15-09:40

Nediljko BUDISA, University of Manitoba

Rewriting the Chemistry of Life: Methodological Frontiers in Genetic Code Expansion

09:40-10:05

Tao LIU, Peking University

TBA

10:05-10:35

Group Photo & Break

10:35-11:00

Kathrin LANG, ETH Zürich

TBA

11:00-11:25

Shixian LIN, Zhejiang University

TBA

11:25-11:50

Ryan A. MEHL, Oregon State University‬‬

TBA

11:50-12:15

Yuzhou WU, Huazhong University of Science and Technology

Expanding the Genetic Code for Engineering Artificial Enzymes

Lunch
12:15-13:45
Session II
13:45-16:55

13:45-14:25

William DEGRADO, University of California, San Francisco

De Novo Design of Small Molecule-Binding Proteins and Enzymes

14:25-14:50

Haiyan LIU, University of Science and Technology of China

De Novo Design of Functional Proteins with SCUBA-T

14:50-15:15

Jiangyun WANG, Institute of Biophysics, Chinese Academy of Sciences

TBA

15:15-15:40

Break  

15:40-16:05

Gerard ROELFES, University of Groningen 

TBA

16:05-16:30

Peilong LU, Westlake University

De Novo Design of Mirror-Image Protein Binders

16:30-16:55

Thomas HUBER, Australian National University

Illuminating Proteins

Poster Session
16:55-18:10
Dinner
18:10-20:00
Day 2
08:00-21:00

08:00-08:30

On-site Registration

Session III
08:30-12:00

08:30-09:10

Jason CHIN, Generative Biology Institute

TBA

09:10-09:35

Demin ZHOU, Peking University

TBA

09:35-10:00

Abhishek CHATTERJEE, Boston College

Reprogramming Translation in Mammalian Cells

10:00-10:20

Break

10:20-10:45

Chang LIU, University of California, Irvine

Extensive Biomolecular Evolution in Vivo

10:45-11:10

Nanxi WANG, Nanjing University of Chinese Medicine

Acylation-Mediated Protein Regulation in Medicinal Plants

11:10-11:35

Bryan DICKINSON, The University of Chicago

Harnessing In Vivo Evolution to Decode and Control Molecular Recognition

11:35-12:00

Xiao XIE, Tsinghua University

TBA

Lunch
12:00-13:30
Session IV
13:30-17:50

13:30-14:10

Jay KEASLING, University of California, Berkeley

TBA

14:10-14:35

Junbiao DAI, Agricultural Genomics Institute at Shenzhen

Machine Learning–Guided Engineering of Yeast eRF1

14:35-15:00

Ahmed BADRAN, The Scripps Research Institute

Programmable Biosynthesis of New-to-Nature Polymers

15:00-15:20

Break

15:20-15:45

Xiaozhou LUO, Shenzhen Institutes of Advanced Technology, CAS

TBA

15:45-16:10

Xue Sherry GAO, University of Pennsylvania

Engineering CRISPR Systems for Precision Therapeutics and Molecular Innovation

16:10-16:35

Haifeng YE, East China Normal University

Synthetic Genetic Control Systems for Smart Living Therapeutics

16:35-17:35

Panel Discussion

Jingyi HOU, EMBO Press

Shushu JIANG, Vita

Yiyun SONG, Nature Chemical Biology

Yingjin YUAN, Tianjin University

17:35-17:50

Closing Remarks and Poster Awards

Peng CHEN, Peking University, Shenzhen Bay Laboratory

GCE Workshop
September 22
September 23
Show All
Overview: Theoretical Foundations and Technical Principles
19:00-21:00

19:00-21:00

Module I. Fundamentals of Genetic Code Expansion and Photo‑crosslinking

Historical development, fundamental principles, and key advantages of genetic code expansion

Applications of genetically encoded photocrosslinking and basic principles of crosslinking mass spectrometry analysis

Hands-on Training: Application of Genetically Encoded Photo-Crosslinking in Protein–Protein Interaction Studies
10:00-18:20

10:00-12:00

Module II. Incorporation and Characterization of Noncanonical Amino Acids

Plasmid construction and transformation strategies

Selection and site-specific incorporation of noncanonical amino acids (ncAAs)

Protein expression, SDS-PAGE analysis, and mass spectrometric characterization

12:00-14:00

Break

14:00-16:00

Module III. Photo‑crosslinking, Chemical Labeling, and Sample Preparation

Photocrosslinking of proteins containing photo-crosslinkers

Click chemistry-based labeling and biotin enrichment

Sample preparation workflows for mass spectrometry

16:00-16:20

Break

16:20-18:20

Module IV. Mass Spectrometry-Based Identification and Data Analysis

Standard workflows for protein identification

Experimental strategies for crosslinking mass spectrometry

Data analysis software and computational workflows

Poster Session

This conference will feature a poster presentation session, with an award for outstanding posters. We sincerely invite you to submit your abstract and participate in the poster presentation (encouraging the display of the latest research advancements or unpublished research topics).

 

How to Participate: Submit abstract for poster when register.

 

Poster Requirements: If you participate in the poster presentation, please print the poster yourself and bring it to the conference venue to be posted in the designated area by the staff.

 

Poster Size: Width 80 cm*Height 120cm

Registration

Registration Deadline: September 17, 2026

 

Please click the Register link at the top of this web page to proceed with the registration process.

 

Registration Fees

*Please upload valid documents for review if you are a student.

 

Notice

1. When making transfers, please include the following note: GCE + [Your Full Name].

2. Please complete the registration and payment before September 17, 2026. Attendees registering on-site will be provided with only the electronic program.

3. The electronic invoice for the registration fee will be sent to the registered email address within 15 working days after the symposium.

 

Refund Policy

1. A 2% administrative fee will be charged for all refund transactions.

2. Refund requests submitted after 18:00 (GMT+8) on September 20, 2026 will not be processed.

Contact Us

Email: symposium@smart.org.cn

Tel: +86-173 2236 4121

Accommodation

We do not provide centralized accommodation for this symposium. Participants can arrange their own accommodation by contacting nearby hotels. (If you encounter any difficulty in booking a hotel, please contact us at symposium@smart.org.cn.)

 

Phishing Alert: Please be alert to fraudulent emails claiming to offer symposium accommodation or hotel services. These phishing attempts may request payment or personal information. If you receive such an email, do not reply, click any links, download attachments, or share any information. We appreciate your vigilance.

 

1. EVEN Hotels Shenzhen Guangming Cloud Park, an IHG Hotel

Address: No. 98 Zhenyuan Road, Guangming District, Shenzhen

The hotel is 200 meters (~3-minute walk) from the conference venue.

Contact: Mr. Zhou, +86-135 0841 8360

 

2. Holiday Inn Express Shenzhen Guangming Cloud Park, an IHG Hotel

Address: No. 98 Zhenyuan Road, Guangming District, Shenzhen

The hotel is 200 meters (~3-minute walk) from the conference venue.

Contact: Mr. Zhou, +86-135 0841 8360

 

3. SYSU Academic Vila, Shenzhen Campus

Address : No.66 Gongchang Road, Guangming District, Shenzhen, Guangdong, China, Guangming District, Shenzhen

The hotel is 2.5 kilometers (~5-minute drive) from the conference venue.

Contact : Mr. Ran, +86-133 3028 2207

 

4. Guangming CIMC Executive Apartments Hotel

Address: CIMC Executive Apartments Hotel, Qiaoming Road, Fenghuang Street, Guangming District, Shenzhen

The hotel is 7.6 kilometers (~20-minute drive) from the conference venue.

Contact: Mr. Lu, +86-138 2659 2644

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